Akademik Veri Yönetim Sistemi
The Journal of Current Pediatrics, cilt.7, ss.96-100, 2009 (Hakemli Dergi)
SUMMARY Colchicine is a drug that has been used primarily in several diseases. Colchicine poisoning is an infrequent but potentially life-threatening problem characterized by multiorgan involvement. We present seven children with colchicine poisoning. Their ages ranged between 1 and 9 years. In six children, the amount of colchicine consumed was between 0.16 and 0.39 mg/kg; the most frequent findings were diarrhea and vomiting. In one patient, the ingested amount was unknown. One of the patients died and all others recovered without sequelae. The severity of colchicine poisoning tends to be related to the dosage of ingested drug and the time of admission to hospital. Symptomatic treatment should be started as soon as possible in colchicine poisoning. (Journal of Current Pediatrics 2009; 7: 96-100) Key words: Colchicine, children, poisoning ÖZET Kolflisin, çeflitli hastal›klar›n tedavisinde primer olarak kullan›lan bir ilaçt›r. Kolflisin zehirlenmesi, s›k görülmemekle birlikte, ço¤ul organ tutulumuna neden olarak hayat› tehdit edici karakterde seyredebilir. Kolflisin zehirlenmesi olan yedi çocuk hasta sunuyoruz. Hastalar›n yafllar› 1 ila 9 aras›nda idi. Alt› hastan›n ald›klar› kolflisin miktarlar› 0,16 mg/kg ile 0,39 mg/kg aras›ndayd›, en s›k görülen bulgu kusma ve ishal idi. Bir hastan›n alm›fl oldu¤u miktar ise bilinmiyordu. Bir hasta kaybedildi, di¤er hastalar ise sekelsiz düzeldi. Kolflisin zehirlenmesinin ciddiyeti, al›nan doza ve hastaneye baflvuru zaman›na ba¤l› görünmektedir. Kolflisin zehirlenmesi sonras›nda mümkün olan en k›sa sürede semptomatik tedavi yap›lmal›d›r. (Güncel Pediatri 2009; 7: 96-100) Anahtar kelimeler: Kolflisin, çocuklar, zehirlenme