Predictive value of early second trimester maternal serum cyclophilin A concentrations in women complicated with preeclampsia: a preliminary case–control study

Celik S., Soyer Çalışkan C.

Hypertension in Pregnancy, cilt.39, sa.4, ss.387-392, 2020 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1080/10641955.2020.1777301
  • Dergi Adı: Hypertension in Pregnancy
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.387-392
  • Anahtar Kelimeler: cyclophilin A, gestational hypertension, predictive models, preeclampsia, Pregnancy
  • Samsun Üniversitesi Adresli: Hayır

Özet

Objective: To investigate cyclophilin A in early second trimester of pregnancy before the onset of preeclampsia. Methods: In this prospective case-control study, 51 pregnant women whose serum were collected and stored and who developed preeclampsia in later follow-up and 41 pregnant women as control group were included. Results: Maternal serum cyclophilin A levels in the study group who developed preeclampsia in later follow-up were significantly higher than those of normal healthy pregnant women. Conclusion: Cyclophilin A may be a valuable predictor for pregnant women who subsequently develop preeclampsia in their pregnancies.