Resistance rates of antituberculosis drugs in pulmonary tuberculosis patients producing mycobacterium tuberculosis Mycobacterium tuberculosis üremesi saptanan akciǧer tüberkülozlu hastaların antitüberküloz ilaçlara direnç oranları

Perincek G., TABAKOĞLU E., Otkun M., ÖZDEMİR L., Özdemir B.

Turk Toraks Dergisi, cilt.12, sa.3, ss.111-113, 2011 (Scopus, TRDizin) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5152/ttd.2011.25
  • Dergi Adı: Turk Toraks Dergisi
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.111-113
  • Anahtar Kelimeler: Mycobacterium tuberculosis, Resistance, Tuberculosis
  • Samsun Üniversitesi Adresli: Hayır

Özet

Objective: Determination of antituberculosis drug resistance rate in pulmonary tuberculosis patients producing Mycobacterium tuberculosis. Material and Method: 134 pulmonary tuberculosis patients producing Mycobacterium tuberculosis in cultures in the Trakya University Medical Faculty Hospital between the years 2005-2007 were enrolled in the study. Four major antituberculosis drugs (H, R, streptomycin (SM), ethambutol (EMB)) resistance and multidrug resistance rates were investigated. using the BACTEC 460 TB system. Results: 134 pulmonary tuberculosis patients producing Mycobacterium tuberculosis were detected and 31 female patients were found and 103 male patients. Acid resistant bacilli were found in 58.2% of the patients with EZN. Antituberculosis resistance rates were established as H 10.4%, R 3%, EMB 0.7%, SM 0.7%. Conclusion: It was determined that a follow up of drug resistance patterns in patients with pulmonary tuberculosis will be useful in determining treatment protocols and preventing drug resistance.