The relationship between ischemia-modified albumin and myocardial infarction in on-pump coronary artery bypass grafting

Menteşe Ü., Doğan O. V., Doğan S., Turan I., Usta S., Demirbaş M., ...Daha Fazla

Turkish Journal of Thoracic and Cardiovascular Surgery, cilt.23, sa.2, ss.245-250, 2015 (SCI-Expanded, Scopus, TRDizin) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5606/tgkdc.dergisi.2015.10641
  • Dergi Adı: Turkish Journal of Thoracic and Cardiovascular Surgery
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.245-250
  • Anahtar Kelimeler: Coronary artery bypass grafting, Ischemia-modified albumin, Perioperative myocardial infarction
  • Samsun Üniversitesi Adresli: Hayır

Özet

Background: This study aims to evaluate the potential of ischemia-modified albumin (IMA) to predict the myocardial infarction in on pump coronary artery bypass grafting (ONCABG) patients. Methods: Fifty elective isolated ONCABG patients (41 males, 9 females; mean age 66 years; range 56 to 75 years) were included in the study. Patients were divided into perioperative myocardial infarction (PMI; n=8) and non-infarction (NPMI; n=42) groups according to perioperative cardiac troponin I (cTnI) values and ECG findings. Serum IMA levels were measured preoperatively, 20 minutes after aortic cross clamping, 30 minutes, at 3, 6, 12 and 24 hours after declamping. Results: Compared to the NPMI group, the declamping 30 minutes, 3, 6 and 12 hours IMA levels were higher in the PMI group (p=0.002, p=0.048, p=0.023, p=0.007, respectively). In both NPMI and PMI groups, the 20 minutes after aortic cross clamping IMA levels were higher compared to the preoperative IMA levels (p=0.0001, p=0.038, respectively). Conclusion: Our study results show that IMA may be an early marker of myocardial infarction in the ONCABG patients.