Hepatitis C virus genotype distribution in patients with chronic hepatitis C in Gaziantep Province Gaziantep bölgesindeki kronik hepatit C hastalarında hepatit C virusu genotip dağılımı


Harman R., GÜNAL Ö., Özger S.

Klimik Dergisi, cilt.30, sa.2, ss.68-70, 2017 (Scopus, TRDizin) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5152/kd.2017.17
  • Dergi Adı: Klimik Dergisi
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.68-70
  • Anahtar Kelimeler: Chronic hepatitis C, Genotype, Hepacivirus
  • Samsun Üniversitesi Adresli: Hayır

Özet

Objective: This study was performed to determine the distribution of age, gender and hepatitis C virus (HCV) genotype in patients followed because of their chronic HCV infection in Gaziantep province and to contribute to the national chronic hepatitis C surveillance efforts. Methods: Anti-HCV-positive patients who applied to our hospital between 2012 and 2016 were included in this study. Their age, gender, HCV RNA positivity and HCV genotype data were recorded retrospectively. Results: A total of 160 patients born and living in Gaziantep province with an average age of 56 years were included in the study. 75% of the patients were in >50 years age group and 25% were in 18-50 years age group. 65% of the patients are female. 157 (98%) patients were found to be infected with HCV genotype 1b. Only one patient was infected with HCV genotype 2 and two patients were infected with HCV genotype 3 were identified. Conclusions: Our findings were compatible with literature data about chronic hepatitis C epidemiology and HCV genotype distribution in Turkey. Only 2 patients were identified as HCV genotype 3 infection in contrary to previous epidemiological data obtained in Kahramanmaraş, a province similar Gaziantep geographically and socioculturally. It was concluded that the evaluations involving Gaziantep province should be expanded to include in multiple centers and multiple patient groups.