Heparin-coated vs. Non-coated cardiopulmonary bypass circuits: Comparing immediate results with different target activated clotting time

Hanedan M. O., Yürük M. A., Arslan A. K., Kılıç A., Sayar U., Mataracı İ.

Brazilian Journal of Cardiovascular Surgery, cilt.35, sa.6, ss.913-917, 2020 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 6
  • Basım Tarihi: 2020
  • Doi Numarası: 10.21470/1678-9741-2019-0387
  • Dergi Adı: Brazilian Journal of Cardiovascular Surgery
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.913-917
  • Anahtar Kelimeler: Cardiac Surgical Procedures, Cardiopulmonary Bypass, Erythrocyte Transfusion, Heparin, Hospital Mortality, Intensive Care Units, Length of Stay, Postoperative Period, Silver
  • Samsun Üniversitesi Adresli: Hayır

Özet

Objective: To compare immediate postoperative results in patients receiving heparin-albumin-coated and non-coated circuits. Methods: A total of 241 patients undergoing on-pump cardiac surgery were divided into two groups: those receiving heparin-coated circuits (Bioline®, Maquet Cardiopulmonary AG., Hirrlingen, Germany) and those receiving non-coated circuits (Maquet Cardiopulmonary AG., Hirrlingen, Germany). Results: Activated clotting times (ACT) during cardiopulmonary bypass (CPB) were significantly shorter in the heparin-albumin-coated group than in the non-coated group (355.64±34.12 vs. 560.38±90.20, respectively, P=0.001). In-hospital mortality and postoperative stroke rates and lengths of intensive care unit stay were similar between the groups; in contrast, in the heparin-albumin-coated group, patients had significantly better outcomes for hospital stay, drainage, and need for erythrocyte transfusion. Conclusion: Heparin-coated circuits and reduced level of systemic heparinization with 300 seconds of target ACT level in cardiac surgery under CPB are safe and result in a very satisfactory clinical course.