Unraveling the Puzzle: Oocyte Maturation Abnormalities (OMAS)

Hatirnaz S., Hatirnaz E., Çelik S., Çalışkan C., Tinelli A., Malvasi A., ...Daha Fazla

Diagnostics, cilt.12, sa.10, 2022 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 12 Sayı: 10
  • Basım Tarihi: 2022
  • Doi Numarası: 10.3390/diagnostics12102501
  • Dergi Adı: Diagnostics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, INSPEC, Directory of Open Access Journals
  • Anahtar Kelimeler: empty follicle syndrome, fertility, FSH, LH, meiosis, meiotic arrest, metaphase, oocyte maturation, oocyte maturation abnormalities, premature ovarian failure, resistant ovarian syndrome, stimulation
  • Samsun Üniversitesi Adresli: Hayır

Özet

Oocyte maturation abnormalities (OMAS) are a poorly understood area of reproductive medicine. Much remains to be understood about how OMAS occur. However, current knowledge has provided some insight into the mechanistic and genetic origins of this syndrome. In this study, current classifications of OMAS syndromes are discussed and areas of inadequacy are highlighted. We explain why empty follicle syndrome, dysmorphic oocytes, some types of premature ovarian insufficiency and resistant ovary syndrome can cause OMAS. We discuss live births in different types of OMAS and when subjects can be offered treatment with autologous oocytes. As such, we present this review of the mechanism and understanding of OMAS to better lead the clinician in understanding this difficult-to-treat diagnosis.