Characterization and investigation of biological properties of silver nanoparticle-doped hydroxyapatite-based surfaces on zirconium

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YILDIZ T., Durdu S., Ozcan K., Usta M.

Scientific Reports, cilt.13, sa.1, 2023 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 1
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1038/s41598-023-33992-5
  • Dergi Adı: Scientific Reports
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Chemical Abstracts Core, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Samsun Üniversitesi Adresli: Evet

Özet

The infections leading to failed implants can be controlled mainly by metal and metal oxide-based nanoparticles. In this work, the randomly distributed AgNPs-doped onto hydroxyapatite-based surfaces were produced on zirconium by micro arc oxidation (MAO) and electrochemical deposition processes. The surfaces were characterized by XRD, SEM, EDX mapping and EDX area and contact angle goniometer. AgNPs-doped MAO surfaces, which is beneficial for bone tissue growth exhibited hydrophilic behaviors. The bioactivity of the AgNPs-doped MAO surfaces is improved compared to bare Zr substrate under SBF conditions. Importantly, the AgNPs-doped MAO surfaces exhibited antimicrobial activity for E. coli and S. aureus compared to control samples.