Can the Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio Be Used to Predict the Risk of Ureteral Stricture Following Ureteroscopy?

---

Aydın M., Küçük E., Ulubay M., Akdeniz E., Atilla M. K.

Endourology Bulletin, cilt.16, sa.3, ss.99-107, 2024 (Hakemli Dergi)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 16 Sayı: 3
• Basım Tarihi: 2024
• Doi Numarası: 10.54233/endourolbull-1526700
• Dergi Adı: Endourology Bulletin
• Sayfa Sayıları: ss.99-107
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• Samsun Üniversitesi Adresli: Evet

Özet

Objective: The purpose of this study was to investigate whether the neutrophil/lymphocyte ratio (NLR) and platelet/

lymphocyte ratio (PLR) can be used to predict the development of ureteral stricture or difficult ureter in patients who

had previously undergone endoscopic upper urinary tract surgery.

Materials and Methods: This observational study was performed between April 2022 and April 2023 at the

Samsun Training and Research Hospital Urology Department, Türkiye. One hundred thirty patients who had

undergone prior endoscopic upper urinary tract surgery were included. These were divided into two groups, with

(Group 1) and without (Group 2) ureteral stricture. The diagnosis of ureteral stricture was based on direct endoscopy

or retrograde pyelography. The groups’ socio-demographic characteristics, clinical data, and NLR and PLR values were

then compared.

Results: The patients’ mean ages were 49.89±14.40 years in Group 1 and 48.92±14.60 in Group 2 (p = 0.704). No

statistically significant differences were observed between the groups in terms of sex, body mass index, or comorbidity.

However, significant differences were determined in terms of passage of kidney stones and numbers of surgical

procedures performed (p = 0.001 and p <0.001, respectively). The groups’ NLR values were 2.62 (0.75-9.18) and 2.29

(0.80-6.67), and their PLR values were 136.57 (55.02-475.45) and 118.66 (37.50-244.17), respectively. The differences

between the groups were not statistically significant (p = 0.139 and p = 0.076, respectively).

Conclusion: Although NLR and PLR values were higher in the group with ureteral stricture in this study, that elevation

was not statistically significant. The results show that the evaluation of NLR and PLR values are not useful in predicting

ureteral stricture in patients who have previously undergone endoscopic upper urinary tract surgery.

Keywords: ureteral stricture, difficult ureter, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio